The Most Unique Restaurants in San Francisco

San Francisco offers a desirable travel destination along the California coastline, chock full of museums, scenic views and eclectic neighborhoods. Not to mention, 'Frisco has one of the most talked-about culinary scenes in the country! San Francisco's dining scene serves up everything from vegan-friendly delight and raw bars to authentic ethnic cuisine. But where are the smartest, savviest diners eating out? Welcome to the Tastemaker Lists. We’ve pulled data from thousands of restaurants to find the most unique restaurants in San Francisco according to OpenTable's most expert, seasoned diners. If in the mood for a memorable meal, check out this list of the most unique restaurants in San Francisco.

The OpenTable Team
Restaurants:Guiso Latin Fusion, Terrapin Creek Cafe & Restaurant, Della Fattoria
Price Range:$$ - $$$$
Cuisines:Latin American, Californian, Farm-to-table
Neighborhoods:Healdsburg, Bodega Bay, Petaluma
Party Size
For 2
Date
Time
7:00 PM

Guiso Latin Fusion

$$$$·Latin American·
Healdsburg
1,210 reviews
  • Fit for Foodies
  • Neighbourhood Gem
  • Outdoor Eating

Guiso Latin Fusion is a family owned bistro-style restaurant in the town of Healdsburg in wine country. For city folk who want a break from the city streets or travelers who are out tasting at the vin...

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Best Value in Wine Country
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Terrapin Creek Cafe & Restaurant

$$$$·Californian·
Bodega Bay
1,629 reviews
  • Fit for Foodies
  • Special Occasion
  • Neighbourhood Gem

Terrapin Creek Cafe and Restaurant is a casual neighborhood spot that locals adore for its convivial atmosphere and festive energy. Located in Bodega Bay, the interior has ochre walls, bold artwork an...

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Best Overall in San Francisco Bay Area
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Della Fattoria

$$$$·Farm-to-table·
Petaluma
222 reviews
  • Local Ingredients
  • Fit for Foodies
  • Creative Cuisine

Della Fattoria is an artisan bread bakery and European style cafe located in Petaluma, California. Open for over 14 years, it has a reputation as one of the best bread bakeries in the whole country. I...

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Walter Hansel Wine Bistro

$$$$·French·
Santa Rosa
1,414 reviews
  • Neighbourhood Gem
  • Special Occasion
  • Good for Anniversaries

Located in the famed roadhouse just west of Santa Rosa, Walter Hansel Bistro is an intimate, cozy restaurant that focuses on quality and customer satisfaction. It’s a French bistro that strips down th...

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French in San Francisco Bay Area
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St. Francis Winery & Vineyards

$$$$·Californian·
Santa Rosa
1,619 reviews
  • Special Occasion
  • Scenic View
  • Fit for Foodies

For a special occasion or big event, it’s great to consider some of the most unique restaurants in San Francisco where you can enjoy even more than the food! St. Francis Winery and Vineyards in Sonoma...

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Best Ambience in San Francisco Bay Area
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Sushi Kosho

$$$$·Sushi·
Sebastopol
229 reviews
  • Fit for Foodies
  • Good for a Date
  • Lunch

Kosho Restaurant at The Barlow is a modern Japanese and sushi restaurant in Sebastopol with a rich, warm interior that is perfect for a romantic date or a dinner with friends. The head chef, Jake Rand...

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Albatross

$$$$·Californian·
Danville
976 reviews
  • Fit for Foodies
  • Special Occasion
  • Outdoor Eating

Albatross is a beautiful modern restaurant with a large dining room, high ceilings and a partially open kitchen to give you a view of the chefs at work. The menu features farm-to-table dishes with bot...

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Juanita & Maude

$$$$·American·
Albany
960 reviews
  • Fit for Foodies
  • Neighbourhood Gem
  • Outdoor Eating

Juanita & Maude, a neighborhood bar run by Chef Scot Eastman offers a unique spin on American cuisine. Located in Albany, in the East Bay, it’s a great escape from the bustle of downtown and is close ...

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American in San Francisco Bay Area

Trading Post Restaurant

$$$$·Farm-to-table·
Cloverdale
370 reviews
  • Local Ingredients
  • Neighbourhood Gem
  • Fit for Foodies

Located in Cloverdale, Trading Post is a casual dining Californian restaurant that has a full bakery right at the restaurant, serving savory treats like brandied onion rolls, potato-arugula focaccia, ...

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Valette

$$$$·Contemporary American·
Healdsburg
2,531 reviews
  • Special Occasion
  • Fit for Foodies
  • Neighbourhood Gem

Valette is a contemporary American restaurant located in Sonoma County that locals consider to be one of the most unique restaurants in San Francisco. The kitchen here focuses on regional offerings fr...

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Contemporary American in San Francisco Bay Area
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Da Flora

$$$$·Italian·
North Beach
158 reviews
  • Neighbourhood Gem
  • Romance
  • Special Occasion

If you’re looking for an experience that is a different speed than your average night out in town, Da Flora in one of the most unique restaurants in San Francisco to find it. Just on the outskirts of ...

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Creekwood Restaurant

$$$$·Italian·
Berkeley
392 reviews
  • Neighbourhood Gem
  • Fit for Foodies
  • Outdoor Eating

Creekwood features a delightful California-Italian menu in a cozy, intimate space with an open kitchen and pizza oven. Located in South Berkeley, it is quickly becoming a favorite of locals in the are...

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Best Value in East Bay

Eight Tables by George Chen

$$$$·Chinese·
Russian Hill
200 reviews
  • Special Occasion
  • Creative Cuisine
  • Tasting Menu

A restaurant of international fame, Eight Tables takes inspiration from the Private Chateau Cuisine dining style, which has popped up all across China. The tasting menu uses the finest seasonal ingred...

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The Hero Ranch Kitchen

$$$$·American·
Saratoga
1,224 reviews
  • Special Occasion
  • Neighbourhood Gem
  • Outdoor Eating

The Hero Ranch Kitchen, located in Saratoga, is the latest restaurant from Angelo Heropoulos. The eatery features eclectic French/California country decor with paneling of reclaimed wood, gorgeous lea...

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American in San Francisco Bay Area